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Publications
2025
Nani J. V., Krenn V., Christoff R. R, Rabello T., Garcez P. P. & Hayashi, M. A. F. RNA-seq transcriptome of ZIKV-infected brain organoids reanalysis implicates Ndel1 oligopeptidase and its cytoskeleton protein binding partners in the infection pathogenesis and recovery following interferon treatment. Brain Research (2025). 149371, https://doi.org/10.1016/j.brainres.2024.149371
Bosone C., Castaldi D., Burkard T.R., Guzman S.J., Wyatt T., Cheroni C., Caporale N., Bajaj S., Bagley J.A., Li C., Sorre B., Villa C.E, Testa G. #, Krenn V.# and Knoblich J.A.# A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids. Nature Methods (2024). https://doi.org/10.1038/s41592-024-02412-5, #corresponding authors
2024
Bosone C., Barilà S.E., Krenn V.# and J.A. Knoblich#. Detailed culture protocol for the generation of human polarized cortical assembloids (polCA). Protocol.io (2024). https://doi.org/10.17504/ protocols.io.4r3l2qyz4l1y/v1. #corresponding authors
2023
Christoff R. R., Nani J. V., Lessa G., Rabello T., Rossi A. D., Krenn V., Higa L. M., Tanuri A., Garcez P. P. & Hayashi, M. A. F. Assessing the role of Ndel1 oligopeptidase activity in congenital Zika syndrome: Potential predictor of congenital syndrome endophenotype and treatment response. Journal of Neurochemistry (2023), 1–14.​https://doi.org/10.1111/jnc.15918
Pajkrt D., Krenn V., Rocha-Pereira J. Editorial: Human organoid technology for virus research, Frontiers in Cellular and Infection Microbiology, VOLUME 13 (2023) doi:10.3389/fcimb.2023.1155252, ISSN=2235-2988
Krenn, V., Higa, L.M., Garcez, P.P. Brain Organoids as a Model to Study Zika Virus and SARS-CoV-2 Infections. In: Gopalakrishnan, J. (eds) Brain Organoid Research. Neuromethods, vol 189. Humana (2023), New York, NY.​doi:10.1007/978-1-0716-2720-4_10
2021
Krenn V., Bosone C., Burkard T.R., Spanier J., Kalinke U., Calistri A., Salata C., Rilo Christoff R., Pestana Garcez P., Mirazimi A., Knoblich J.A. Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell (2021) 28, 1362–1379.e7.doi:10.1016/j.stem.2021.03.004
Bajaj, S., Bagley, J.A., Sommer, C., Vertesy, A., Nagumo Wong, S., Krenn, V., Lévi-Strauss, J., Knoblich, J.A. Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. (2021) 40, e108714. ​doi:10.15252/embj.2021108714
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